中晚期乳腺单纯癌粗面内质网及核糖体的形态参数的逐步判别分析

STEPWISE DISCRIMINATORY ANALYSIS OF MORPHOLOGICPARAMETERS OF THE ROUGH ENDOPLASMIC RETICULUM ANDRIDOSOME IN INTERMEDIATE AND LATE STAGE SIMPLE BREAST CANCER

目的:探讨乳腺单纯癌临床诊断的量化标准。方法:对20例中期和20例晚期乳腺单纯癌癌细胞粗面内质网、游离核糖体、多核糖体的7个形态参数进行体视学分析,用逐步判别分析法剔选各参数值,建立判别函数。结果:Vvr2、Svr2、SR与Sr2之间有显著性差异（P<0.01）,回代判别正确率达到85.7％。结论:本研究建立的乳腺单纯癌临床诊断量化标准对鉴别诊断乳腺癌及判断其恶性程度和预后具有重要意义。

Aim: To study the quantitative standards for the clinical diagnosis of simple breast cancer. Methods: A stereological analysis was made for the 7 morphological parameters of rough endoplasmic reticu-lum, free ribosome and polyribosome in 20-cases of intermediate simple breast cancer and 20 cases of late simple breast cancer. The discrimination function was determined by picking out all the parameters with stepwise discriminatory analysis. Results: Significant difference was found among Vvr2, Svr2, SR and Sr2; the total discrimination ratio was 85.7%. Conclusions: The quantitative standards for the clinical diagnosis of simple breast cancer established in our study is of important significance for the differential diagnosis of breast cancer as well as its malignancy and prognosis.