血液成分制剂抗血栓药人活化C蛋白(CTC-111) 被引量：1

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摘要 1 商品名 Anact C2 化学名活性蛋白 C（APC）是由155个氨基酸残基组成的轻链（25kDa）及250个氨基酸残基组成的重链（按所连接的糖链不同分以下3种:α链42kDa、β链37kDa和γ链34kDa）通过二硫键连接而成的双链糖蛋白。

作者戴经铨

出处《国外医药（合成药．生化药．制剂分册）》 2002年第4期248-248,共1页 World Pharmacy

关键词抗血栓药人活化C蛋白药理学药物适应证剂量

同被引文献6

1Carroll LR. Servere sepsis, clinical presentation, pathophysiology,and treatment[J]. US Pharmacist, 2002,Auguest: HS3-10.
2Pastores SM. Drotrecogin alfa (activated) a novel therapeutic strategy for severe sepsis[J]. PMJ, 2003,79(1):5-10.
3Taylor FB Jr, Cheng-Hock T, Hoots WK, et al. Towards definition, clinical and laboratory criteria and a scoring system for disseminated introvascular coagulation[J]. Thromb Haemost, 2001,86:1327-1330.
4Esmon TC. Protein C antioagulant pathway and its role in controlling microvascular thrombosis and inflammation[J ]. Grit Care med,2001,29: 48-52.
5Bernard GR, Vincent JL, Laterre PF, et al. Efficacy and safety of recombinant human activated protein C for severe sepsis[J]. N Engl J Med, 2001,344:699-709.
6Marcin R, Boiena S, Iwona R, et al. Recombinant human activated protein C for severe sepsis in a neonate[J]. Med Sci Monit, 2002,8(11) :CS90-94.

2002年第4期

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