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绝经后骨质疏松发生的分子机制 被引量:5

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摘要 绝经后雌激素的减少导致血源性生长因子与干细胞、单核细胞和淋巴细胞产生的炎症前细胞因子增多 ,并对核因子 (NF) κB配基的受体激活剂抑制作用减弱 ,从而刺激骨髓的破骨细胞前体———粒细胞巨噬细胞 集落形成单位 (GM CFU)分化成为破骨细胞。当破骨细胞形成过多 。
作者 朱梅 邱明才
出处 《国外医学(内分泌学分册)》 2002年第4期226-229,共4页 Foreign Medical Sciences(Section of Endocrinology)
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