喘息性支气管炎、哮喘及肺炎患儿红细胞免疫功能变化的比较

COMPARISION OF IMMUNE FUNCTION OF RED BLOOD CELLS IN CHILDREN PATIENTS WITH ASTHMATOID BRONCHITIS,ASTHMA OR PNEUMONIA

目的 :观察小儿喘息性支气管炎 (喘支 )、哮喘、肺炎红细胞免疫功能的变化。方法 :对喘支 60例、哮喘 40例、肺炎 2 0例年龄 1～ 4岁的患儿急性期和恢复期的血液标本进行红细胞 C3 b( RBC- C3 b)受体花环率和红细胞免疫复合物 ( RBC- IC)花环率检测。结果 :小儿肺炎急性期与对照组比较 ,RBC- C3 b受体花环率具有极显著性差异 ( P<0 .0 0 1 ) ,RBC- IC花环率差异有显著性 ( P<0 .0 5 )。喘支急性期 RBC- C3 b受体花环率较对照组差异无显著性 ( P>0 .0 5 ) ,而 RBC- IC较对照组有极显著性差异 ( P<0 .0 0 1 )。哮喘急性期 RBC- C3 b、RBC- IC较对照组均具有极显著性差异 ( P<0 .0 0 1 )。结论 :本试验对小儿喘支、哮喘、肺炎的病因、发病机制的研究提供重要线索 ,为治疗提供依据 。

Objective:To observe the red blood cells immune function in children patients with asthmatoid bronchitis,asthma or pneumonia.Methods:The blood samples at the stages of acuteness and convalescence in children patients who were one to four years old,60 with asthmatoid bronchitis,40 with asthma,and 20 with pneumonia,were detected for RBC C 3b acceptor garland rate and RBC IC garland rate.Results:There was a significant difference in RBC C 3b receptor garland rate between healthy controls and children at the acute stage of pneumonia( P <0 001),and so was in RBC IC garland rate( P <0 05).There was an obvious difference in RBC ICs between controls and children at the acute stage of asthmatoid bronchitis( P <0 001),but there was not in RBC C 3b receptor garland rate( P >0 05).RBC C 3b and RBC IC differed evidently between controls and children at the acute stage of asthma( P <0 001, P <0 001).Couclusion:The two measurements have an important significance for investigation of pathogenesis and mechanism of and in treatment for asthmatoid bronchitis,asthma,and pneumonia in children.