微生物来源的黑色素生物合成抑制剂H7264A和B的分离和鉴别

Isolation and structure elucidation of melanin biosynthesis inhibitors H7264 A and B

利用直接抑制产黑色素菌株产生黑色素的方法 ,从链霉菌 sp.H72 6 4的次生代谢产物中分离到两个黑色素生物合成抑制剂 H72 6 4 A和 B,经理化性质和光谱分析 ,它们与 Enopeptin A和 B同质。

H7264 A and B, melanin biosynthesis inhibitor, were isolated from fermentation broth of Streptomyces sp. H7264. The physico chemical properities and spectroscopic analyses of the two active compounds revealed that H7264 A and B were identical with enopeptin A and B.