期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

Ig融合蛋白的应用研究进展 被引量：3

Progress on Ig Fusion Proteins Application
下载PDF
导出
摘要 Ig融合蛋白是指在基因水平将目的基因同Ig部分片段基因相连 ,克隆并表达的重组蛋白。该蛋白具有目的蛋白的功能 ,又获取Ig的新特性。本文综述了Fab融合蛋白及Fc融合蛋白在临床及科学研究应用方面的进展。 Ig fusion proteins are kinds of recombinant proteins in which on gene level the aimed genes were linked with Ig partial coding sequence, and then the fused genes was cloned and expressed. These recombinant proteins have the functions of aim protein and the characters of Ig. The application development of Fab and Fc fusion protein in clinic and sciences research are reviewed in this paper.\;
作者 周素芳 黄秉仁
机构地区 中国医学科学院基础医学研究所 广西医科大学生化教研室
出处 《中国生物工程杂志》 CAS CSCD 2002年第3期45-49,共5页 China Biotechnology
关键词 IG融合蛋白 应用 研究进展 免疫球蛋白 Immunoglobulin, Fusion Protein
分类号 R392－33 [医药卫生—免疫学] R394.8 [医药卫生—医学遗传学]
  • 相关文献

参考文献31

  • 1Forsberg G, Ohlsson L, Brodin T et al. Br J Cancer, 2001, 85(1):129- 136
  • 2Liao S, Khare PD, Arakawa Fet al. Anticancer Res, 2001,21(3B): 1673 - 1680
  • 3Marshall KW, Marks JD. J Immunother ,2001,24( 1 ) :27 - 36
  • 4Wang L, Liu B, Schmidt M et al. Prostate, 2001,47 ( 1 ): 21 - 28
  • 5Wallace PK, Tsang KY, Goldstein J et al. J lmmunol Methods,2001,248( 1 - 2): 183 - 94
  • 6Simon A, van Deuren M, Tighe PJ et al. Arch Intern Med,2001,161 (20) :2491 - 2493
  • 7Kyriakides C, Favuzza J, Wang Y et al. Br J Surg, 2001,88(6):825 - 830
  • 8Emmanuilidis K, Weighardt H, Maier S, Gerauer K et al. J Immunol,2001,167(7) :3919 - 27
  • 9Barouch DH, Fu T, Montefiori DC et al. Immunol Lett, 2001,79(1 -2):57-61
  • 10CraiuA, Barouch DH,Zheng xx et al. AIDS Res Hum Retroviruses,2001,17(10): 873 - 86.

同被引文献25

  • 1金锋,王舒宝.重组人白介素—2Ⅰ期临床试验报告[J].实用肿瘤学杂志,1995,9(3):20-21. 被引量：2
  • 2PENICHETM L, CRUZDJS, SUS, etal. [J]. Human Antibodies, 2001, 10: 43-49.
  • 3HORNICK J L, KHAWLI L A, HU P, et al. [J]. Clinical Cancer Research, 1999, 5(1): 51 - 60.
  • 4ROYAL R E, STEINBERG S M, KROUSE R S, et al. [J]. Cancer J Sci Am, 1996, 2(2): 91.
  • 5SOGAARD M, ANDERSEN J S, ROEPSTORFF P, et al. [J]. Biotechnology(N Y, 1993, 11: 1162- 1165.
  • 6Stephens F,Bick DA.National pilot to implement pressure ulceguidelines;results of the baseline audit.Br J Community Nurs,2002,9:4.
  • 7Takeuchi K,Lamb R A.Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport[J].J Virol,1994,68(2):911-919.
  • 8Krystyna M,Jinqi F,Mark E,et al.Induction of influenza type A virus specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodo mains of matrix protein 2[J].Vaccine,2003,21(20):2616-2626.
  • 9Liu W L,Li H,Chen Y H.N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication[J].FEMS Immunology and Medical Microbiology,2003,35(2):141-146.
  • 10Liu W L,Zou P,Liu Z Q,et al.High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity[J].Vaccine,2004,23(3):366-371.

引证文献3

二级引证文献10

中国生物工程杂志
2002年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部