兔膝关节半月板形态结构增龄性变化的初步观察

The Morphological Changes of Meniscus of Rabbits' Knee Joints with Age

为探讨半月板形态结构增龄性变化 ,采用扫描电镜和光镜观察了 1月龄、1年龄和3 .5年龄兔半月板形态结构。结果 :电镜下见软骨细胞成串位于陷窝内 ,以 1月龄多见 ,随年龄增加明显减少。半月板的表面呈现条状的隆起 ,随着年龄增加逐渐变细且短小。各年龄组半月板表面皆可见微细的小孔或空隙区 ,这些小孔或空隙区随年龄增加而减小。光镜下见半月板水平切面 :1月龄兔血管丰富 ,1年龄、3 .5年龄兔只在半月板周边和外 1 /3处有血管分布。胶原纤维随增龄而由稀少转为成束排列。结果提示各年龄段半月板在代谢、营养供应、修复再生等方面都存在一定的差异。

To study the morphological changes of meniscus with age, the meniscus from rabbits' knee joint at the age of 1 months, 1 year and 3.5 years old were observed by light and electron microscopy. The results showed that the cartilage cells of meniscus lying in bead were located in lacunaes, there was a trenchancy of quantity of cartilage cells decreasing with the ages increasing. The formed eminences could be observed in superficies of the meniscus in one year old rabbit, they became even with the ages increasing. At the same time, very small holes and horrow areas were also observed in superficies of the meniscus, and became smaller with the ages increasing. The vessels were abundant in the meniscus of the rabbits of 1-month-old, but only in periphery and one third of lateral areas in the meniscus vessels could be observed in the rabbits of 1 year old and 3.5 years old. Collagen's fibers became fascicularly lined from sparse with the ages increasing. It was shows that the meniscus are different at each age in metabolism, nourishment supply and repair.