摘要
目的探讨门脉高压性胃病(PHG)的病理特点,分析PHG的影响因素。材料方法对36例肝炎后肝硬化PHG患者的胃黏膜活检组织光、电镜下观察并进行幽门螺杆菌特殊染色,乙型肝炎病毒(HBV)表面抗原(HBsAg)和核心抗原(HBcAg)免疫组化染色。结果胃黏膜血管扩张、内皮细胞连接松散、黏膜上皮和间质水肿等血管病变是PHG共同的病理改变。幽门螺杆菌(HP)感染率为77.8％(28/36),而胃黏膜乙型肝炎病毒(HBV)感染对PHG影响的证据不足。结论 PHG有其较特征性的病理改变;幽门螺杆菌感染和高酸可能是影响PHG的重要因素,抗感染和抗酸治疗有其理论基础。
Aim To explore the characteristics of
pathology of portal hypertension gastropathy (PHG) and to
analysis the associated factors of PHG. Methods Gastric mu-
cosal tissues from 36 patients with PHG were observed under
light and electron microscopy, and immunohistochemistry and
special stain were also performed for HBsAg and HBcAg. Re-
sults Vascular changes of the gastric mucosa were the basic
histology of PHG, and helicobacter pylori (HP) infection was
common in PHG (77. 8 % ). But there wasn't enough evidence
to prove that infection of HBV was related with the course of
PHG. Conclusions PHG has its own pathological characteris-
tics; HP and high acid state may be two important influential
factors of PHG.
出处
《传染病信息》
2002年第2期70-70,共1页
Infectious Disease Information
