氟西汀治疗强迫症双盲自身对照研究

Double-blind Self-control of Fluoxetine in Obsessive-compulsive Disorder(OCD).

为进一步研究氟西汀治疗强迫症的疗效 ,对我院 1 999年 2月～ 2 0 0 0年 2月间住院并符合 CCMD-2 -R诊断标准的强迫症 ( OCD)患者 1 7例 ,进行双盲自身交叉对照研究 ,结果在试验进行到第 1 0例时 ,试验线跨越 U线 ,A药 (氟西汀 )显著优于 B药 (淀粉 ) ,经 Ridit分析 ,前后自身对照有显著性差异 ,说明氟西汀对强迫症确有较好的疗效。

In order to further study the curative effect of fluoxetine in the treatment of OCD,the double-blind self-cross control studies were made in 17 patients with phobia who were admitted in our hospital from Feb.1999 to Dec.2000.The 10th Patient was studied,the line of experiment was beyond U line.A drug(fluoxetine)was significantly dominant over B(starch).According to Ridit analysis,there was obvious difference between the pre-and post-self control,which suggested fluoxetine did have better curative effect in the treatment of phobia.