铜陵市发热出疹性疾病血清流行病学分析

Sero-epidemiological Analysis of Rash and Fever Illness in Tongling City

目的 为了解发热出疹性疾病 (RFls)血清流行病学特征 ,以便更好地开展麻疹监测。方法 1998～2 0 0 1年 ,在铜陵市采集了爆发和散发病例的急性期血清标本 ,用酶联免疫吸附试验 (ELISA)捕捉法检测麻疹和风疹IgM抗体。结果 74例中麻疹IgM抗体阳性 15例 (2 0 .2 7% ) ;风疹IgM抗体阳性 15例 (2 0 .2 7% )。RFls病例的发病高峰为春夏季 ;15例麻疹IgM抗体阳性病例中 ,有免疫接种史者占 6 0 .0 0 % (9/ 15 ) ,免疫史不详和无免疫史者占 4 0 % (6 / 15 )。结论 血清学诊断是科学鉴别RFls的重要手段 ;加强麻疹疫苗的有效接种和强化免疫 。

Objetive In order to understand sero-epidemiological characteristics of rash and carry out measles surveillance well.Methods we collected acute phase serum specimens of epidemic and sporadic RFIs in Tongling City from 1998～2001 and tested for measles IgM and rubella IgM antibody by capatued-ELISA. Results The results indicated that 15 measles cases (20.27%) and 15 rubella cases (20.27%) of 74 RFIs surveyed were diagnosed. The seasonal peaks of measles and rubella of RFIs cases were very noticeable with incidence increasing at the end of spring and the summer. Of 15 M-IgM antibody positive cases, 6 cases were not vaccinated or not clear, accounting for 40%. Conclusions We hold that sero-diagnosis is the important measures to distinguish RFIs. Effective and supplementary measles vaccination is the major strategy to speed up measles control.