补肾延寿胶囊抗衰老作用

Antisenescent action of capsule bushenyanshou

目的 观察补肾延寿胶囊对实验动物抗氧化功能、耐寒及抗疲劳功能的影响。方法 检测补肾延寿胶囊对老龄大鼠血红细胞超氧化物歧化酶（ＳＯＤ）、组织丙二醛（ＭＤＡ）含量以及阳虚症小鼠体重、体温和冰水游泳时间的影响。结果 补肾延寿胶囊（０．４、０．８ ｇ／ｋｇ ｉｇ，ｑｄ× ２１日）既能升高老龄 ＳＤ大鼠血红细胞 ＳＯＤ比活性，明显降低肝和脑组织 ＭＤＡ含量，也能增加氢化泼尼松所致阳虚症小鼠的体重、体温和冰水游泳时间。结论 结合补肾延寿胶囊对免疫功能的增强和调节作用，提示补肾延寿胶囊具有一定的抗衰老作用。

The effect of capsule bushenyanshou (BSYS) on the antioxidative function, and the tolerance of cold and fatigue in rats was investigated. Methods The activity of erythro-cytic superoxide dismutase (SOD), the contents of brain and liver malondialdehyde (MDA) in rats and the changes of body weight, body temperature and the swimming time at 0℃ in mice were measured. Results Capsule BSYS(400, 800 mg/ kg, ig, qd X 21d) increased erythrocytic SOD activity and markedly reduced brain and liver homogenate MDA contents in ole rat and enhanced the body weight and body temperature, and prolonged the swimming time at 0℃ in hydrocortisone -treated(15 mg/ kg, sc, qd × 5 d) mice. Conclusion Capsule BSYS has a certain antisenescent action.