海洋真菌及其活性物质的研究概况

Progress of studies on marine filamentous fungi and their bioactive substances

海洋微生物种类繁多 ,是筛选新药的丰富资源宝库 .陆地真菌是仅次于放线菌的多产抗生素的微生物类群 ,而海洋真菌正在成为海洋药源微生物研究的新热点 .海洋真菌产生的生物活性物质已经引起研究者的关注 ,并将成为海洋药物的重要来源 .本文结合国内外文献报道 ,阐述了海洋真菌及其活性物质的研究情况 .

The diversity of marine microorganisms provides a luxuriant resource for screening new drugs. Marine filamentous fungi are becoming a hot research field in studies of marine microorganisms for potential pharmaceutical application, whereas terrestrial ones were the second possible producer next to actinomycetales for antibiotics in the land. Some novel bioactive substances have been found derived from marine filamentous fungi, therefore the fungi must be an important resource of marine drugs. Current outcrops of researching marine filamentous fungi and their bioactive secondary metabolites are surveyed in present paper.