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基因治疗的研究现状与评价 被引量:13

基因治疗的研究现状与评价
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出处 《中华肿瘤杂志》 CAS CSCD 北大核心 2002年第4期313-315,共3页 Chinese Journal of Oncology
关键词 基因治疗 临床试验 恶性肿瘤 单基因遗传病 基因转运系统 Gene therapy Clinical trial Gene transfer
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  • 1高晓康,李青,王禾,杨波,袁建林,邵国兴,康福霞.反义survivin基因对786-O细胞的体外作用及其对表阿霉素诱导细胞凋亡作用的观察[J].中华肿瘤杂志,2005,27(8):468-470. 被引量:12
  • 2Marsh JW, Finkelstein SD, Schwartz ME, et al. Advancing the diagnosis and treatment of hepatoeellular carcinoma [J]. Liver Transpl, 2005, 11(4): 469-72.
  • 3Portsmouth D, Hlavaty J, Renner M. Suicide genes for cancer therapy [J]. Mol Aspects Med, 2007, 28 (1): 4-41.
  • 4Altaner C. Prodrug cancer gene therapy[J]. Cancer Lett, 2008, 270 (2): 191-201.
  • 5Stefani AL, Barzon L, Castagliuolo I, et al. Systemic efficacy of combined suicide/cytokine gene therapy in a murine model of hepatocellular carcinoma[ J ]. Hepatol, 2005, 42(5): 728-35.
  • 6Majumdar AS, Hughes DE, Lichtsteiner SP, et al. The telomerase reverse transeriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters [J]. Gene Ther, 2001, 8(7): 568-78.
  • 7Bonini C, Ferrari G, Verzeletti F, et al. ADV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia [J]. Science, 1997, 276: 1719-22.
  • 8Sterman DH, Treat J, Litzky LA, et al. Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma [J]. Huanm Gene Ther, 1998,9: 1083-92.
  • 9ZHOU JF, GAO QL, CHEN G, et al. Novel oncolytic adenovirus selectively targets tumor-associated polo-like kinase 1 and minor cell viability[J ]. Clin Cancer Res, 2005, 11 : 8431-40.
  • 10AltanerC. Prodrug cancer gene therapy[J]. CancerLett, 2008, 270(2) ; 191-201.

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