降纤酶与低分子肝素钙对急性脑梗死疗效的分析

Comparisons Between the Therapeutic Effects of Defibrase and Low Molecular Weight Heparin(LMWH)on Acute Cerebral Infarction

通过对急性脑梗死患者 5 2例的随机分组 ,降纤酶治疗组与低分子肝素钙治疗组各为 2 6例 ,均在发病后 4 8h内给药 ,并在治疗前后对神经功能缺损程度进行评分 ,比较降纤酶与低分子肝素钙治疗急性脑梗死的疗效。结果是降纤酶组的患者痊愈率为 30 .7% ,较低分子肝素钙组的 15 .4 %显著地高出了 15 .3% ;在 14天和 2 1天时 ,降纤酶治疗组的患者神经功能缺损的恢复较低分子肝素钙组分别高出 19.0 %和 2 5 .8% ,表现出明显的优势效果 ,即降纤酶药物较低分子肝素钙对于急性脑梗死患者的治疗 ,无论是在神经功能缺损恢复的速度上 。

The paper objectively analyses the defibrase and LMWH therapeutic efficacy on acute cerebral infarctions.52 cases suffering from acute cerebral infarctions were selected. The defibrase group was composed of 26 cases.The other 26 cases were selected as LMWH group. All of the 52 cases were given drugs during 48 hours in hospital. The patients' neurologic functional defieiency were measured before the treatment and after. Results showed that the curative rate in defibrase group was significantly higher than that in LMWH group (P<0.05). And the patients' neurologic functional deficiency of the defibrase group decreases significantly after treatment (P<0.05 ).Defibrase can inhibit thrombosis and fasten hemdysis, nevertheless LMWH can inhibit thrombosis, and influence slightly blood coagulation fibrin solution system.Defibrase treatment can significantly deplete clinical symptoms.