安徽省120922例宫颈癌筛查分析

Analysis of 120922 cases of cervical cancer screening in Anhui province

目的评估改良巴氏涂片的效果并研究宫颈癌高危人群年龄分布特点、地区差异,为安徽省普查方案的制定提供参考。方法采用改良巴氏涂片法取材,分析细胞学和组织学诊断的符合率。数据采取χ2检验和相关分析,计算阳性率、构成比及各级病变的年龄别发病率,比较发病率的差异性。结果 ASC-US/ASG-US与病理的符合率为50.1%,ASC-H与病理的符合率为70.7%,LSIL与病理的符合率为72.8%,HSIL与病理的符合率为90.5%。样本总阳性率为2.69%,太湖3.80%,宁国3.36%,与其他3个地区相比差异有统计学意义。宫颈癌年龄别患病率:35岁以下年龄组为1.58%,36~40岁年龄组为2.45%,41~45岁年龄组为2.34%,46~50岁年龄组为2.84%,51~55岁年龄组为2.86%,56~60岁年龄组为2.76%,61~65岁年龄组为2.56%,大于65岁年龄组为3.08%,随年龄的增长成趋势性增加(R2=0.6034,P=0.023)。结论改良巴氏涂片可以作为宫颈癌筛查的手段,建议筛查的起始年龄应在35岁以下,终止年龄放宽至65岁以上,同时加大对皖南山区普查力度。

Objective To study the age distribution of the population at high risk of cervical cancer and regional differences in Anhui province.Exploring the value of improved Pap smear screening.Methods Using improved Pap smear collects specimens.Using chi-square test and correlation analysis calculate the positive rate and the age structure of disease incidence.Comparing the morbidity differences and analysing the coincidence of cytological and histological.Results The positive rate of the sample is 2.69%;Taihu is county 3.80%;Ningguo county is 3.36%,compared with the other three regional differences are statistically significant.Coincidence of ASC-US/ASG-US is 50.1%;ASC-H is 70.7%;LSIL is 72.8%;HSIL is 90.5%.Age-specific prevalence of cervical cancer age-specific prevalence of≤35 age group is 1.58%;36~40 age group is 2.45%;41 ~45 age group is 2.34%;46~50 age group is 2.84 %;51 ~55 age group is 2.86%;56 ~60 age group is 2.76%;61 ~65 age group is 2.56%;>65 age group is 3.08%.The prevalence is ascending while age increasing(R2 =0.6034, P=0.023).Conclusion The improved Pap smear screening is a appropriate method for cervical cancer.Pap smear screening starting age should be under 35 years old and terminating age above 65 years old.Strengthen efforts to cervical cancer screening in southern mountains of Anhui Province.