高龄结直肠癌患者根治性手术的危险因素分析

Analysis of risk factors of radical opration in elderly colorectal cancer patients

目的探讨高龄结直肠癌患者根治性手术的危险因素。方法回顾性分析238例行根治性结、直肠癌手术的高龄(≥70岁)患者的临床资料,分析影响短期手术效果的危险因素。结果高龄结直肠癌患者合并基础疾病发生率高[158例(66.4%)],术后并发症发生率高[99例(41.6%)],最常见的并发症是肺部感染和切口感染。多因素分析显示:年龄≥76岁、BMI≥23 kg/m2、合并基础疾病、手术时间、联合脏器切除、术前贫血、低蛋白血症是高龄结直肠癌患者的手术危险因素。结论高龄结直肠癌患者术前合并症、手术并发症多,临床医生应重视围手术期处理以减少患者术后并发症,改善总体预后。

Objective To investigate the risk factors of radical surgery in the treatment of elderly patients with colorectal cancer. Methods To analyze the risk factors of short-term surgical results,a retrospective analysis was used to study the clinical information of 238 cases(≥70 years)underwent radical colorectal cancer surgery in our hospital from January 2008 to December 2012.Results The incidence was high in 158 cases of colorectal cancer patients with underlying diseases(66.4%),and the incidence of postoperative complications was high in 99 cases(41.6%).Of them,the most common complications were pulmonary infection and wound infection.Multivariate analysis showed that:Age≥76,BMI≥23,on a basis of underlying diseases,operation time,combined organ resection,preoperative anemia and hy-poproteinemia were the operation risk factors for colorectal cancer in elderly patients.Conclusion Clinical surgeons should pay more atten-tion to reducing the postoperative complications in elderly patients with colorectal cancer who are subject to preoperative and operation compli-cations.