期刊文献+

LDL-C/HDL-C及TG/HDL-C比值与冠状动脉病变程度的相关性研究 被引量:11

Research of correlation between LDL-C / HDL-C and TG / HDL-C ratio and severity of coronary heart disease
下载PDF
导出
摘要 目的探讨LDL-C/HDL-C及TG/HDL-C比值与冠心病病变程度之间的相关性。方法分析169例冠脉造影检查确诊的冠心病患者(CHD组)及103例冠脉造影结果阴性者(对照组)LDL-C/HDL-C及TG/HDL-C比值与冠心病及其病变程度的关系。结果冠心病组患者LDL-C/HDL-C比值及TG/HDL-C比值水平及异常率均明显高于对照组,相关分析显示:LDLC/HDL-C及TG/HDL-C比值与冠心病及其病变程度均呈正相关,而前者预测意义更大。结论 LDL-C/HDL-C及TG/HDL-C比值可作为预测CHD的指标,且LDL-C/HDL-C比值水平与CHD相关性更强。 Objective To explore the correlation between LDL-C/HDL-C and TG/HDL-C ratio and severity of coronary heart disease. Methods LDL-C / HDL-C and TG / HDL-C ratio was analysed in 272 geriatric cases that underwent coronary angiography,who were positive in 169 geriatric patients( CHD group),and negative in 103 cases( normal control group). Results Both LDL-C / HDL-C and TG / HDL-C ratio and its abnormal rate were significantly higher in patients with CHD than those in the normal control group( P < 0. 05). Correlation analysis and multivariate regression analysis revealed that the ratio had significant positive correlation with coronary heart disease and its severity.Conclusion LDL-C / HDL-C and TG / HDL-C ratio is a good predictive index for CHD. Compared to TG / HDL-C ratio,LDL-C / HDL-C ratio reveals stronger correlation with CHD.
出处 《安徽医学》 2015年第1期75-77,共3页 Anhui Medical Journal
关键词 冠心病 低密度脂蛋白胆固醇 高密度脂蛋白胆固醇 三酰甘油 心血管风险 Coronary heart disease Low density lipoprotein cholesterol High density lipoprotein cholesterol Triglyceride Cardio-vascular risk
  • 相关文献

参考文献7

  • 1Uthoff H,Staub D,Socrates T,Meyerhans A,Bundi B,Schmid H P,Frauchiger B.PROCAM-, FRAMINGHAM-, SCORE- and SMART-risk score for predicting cardiovascular morbidity and mortality in patients with overt atherosclerosis. VASA. Zeitschrift für Gef?sskrankheiten. Journal for vascular diseases . 2010
  • 2Kasai T,Miyauchi K,Yanagisawa N,et al.Mortality risk of triglyceride levels in patients with coronary artery disease. Heart . 2013
  • 3Boumaiza Imen,Omezzine Asma,Rejeb Jihene,Rebhi Lamia,Kalboussi Nesrine,Ben Rejeb Nabila,Nabli Naoufel,Ben Abdelaziz Ahmed,Boughazala Essia,Bouslama Ali.Apolipoprotein B and non-high-density lipoprotein cholesterol are better risk markers for coronary artery disease than low-density lipoprotein cholesterol in hypertriglyceridemic metabolic syndrome patients. Metabolic syndrome and related disorders . 2010
  • 4Di Angelantonio E.,Sarwar N.,Perry P.,Kaptoge S.,Ray K.K.,Thompson A.,Wood A.M.,Danesh J.,Lewington S.,Collins R.,Sattar N.,Packard C.J.,Thompson S.G.Major lipids, apolipoproteins, and risk of vascular disease. JAMA - Journal of the American Medical Association . 2009
  • 5赵水平.高甘油三酯与冠心病风险的相关性[J].中华心血管病杂志,2011,39(9):789-790. 被引量:18
  • 6刘梅颜,郭丹杰,胡大一,徐成斌,崔永东.LDL-C/HDL-C及TG/HDL-C比值对冠心病的预测价值的评价[J].中国医刊,2002,37(5):32-34. 被引量:19
  • 7赵尚敏,张明,霍海洋,何青.甘油三酯/高密度脂蛋白胆固醇比值对老年冠心病诊断价值的探讨[J].心血管康复医学杂志,2000,9(2):15-17. 被引量:9

二级参考文献18

  • 1徐成斌.冠心病防治在调脂领域的某些进展与动向.心脑血管疾病危险因素控制学术研讨会[M].,2001.7-10.
  • 2Assmann G,Schulte H,Cullen P,et al.Assessing risk of myocardial infarction and stroke:new data from the prospective cardiovascular Münster (PROCAM) study. Eur J Clin Invest,2007,37:925-932.
  • 3Sarwar N,Danesh J,Eiriksdottir G,et al.Triglycerides and the risk of coronary heart disease: 10,158 incident cases among 262,525 participants in 29 Western prospective studies.Circulation,2007,115:450-458.
  • 4Emerging Risk Factors Collaboration,Di Angelantonio E,Sarwar N,et al. Major lipids,apolipoproteins,and risk of vascular disease.JAMA,2009,302:1993-2000.
  • 5Vine DF,Takechi R,Russell JC,et al.Impaired postprandial apolipoprotein-B48 metabolism in the obese, insulin-resistant JCR:LA-cp rat: increased atherogenicity for the metabolic syndrome.Atherosclerosis,2007,190:282-290.
  • 6Weinstein MM,Yin L,Tu Y,et al.Chylomicronemia elicits atherosclerosis in mice-brief report.Arterioscler Thromb Vasc Biol,2010,30:20-23.
  • 7Liu L,Wen T,Zheng XY,et al.Remnant-like particles accelerate endothelial progenitor cells senescence and induce cellular dysfunction via an oxidative mechanism. Atheroeclerosis,2009,202:405-414.
  • 8Keech A,Simes RJ, Barter P,et al.Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial.Lancet,2005,366:1849-1861.
  • 9Jialal I, Amess W, Kaur M, et al. Management of hypertriglyceridemia in the diabetic patient. Curr Diab Rep,2010,10:316-320.
  • 10Miller M,Stone NJ,Ballantyne C,et al.Triglycerides and cardiovascular disease:a scientific statement from the american heart association.Circulation,2011,123:2292-2333.

共引文献43

同被引文献85

引证文献11

二级引证文献77

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部