冷冻联合氩气刀介入治疗恶性气道狭窄的临床观察

Clinical observation of cryotherapy combined with argon knife in interventional treatment of malignant tracheobronchial stenosis

目的探讨冷冻联合氩气刀介入治疗恶性气道狭窄的临床疗效及安全性。方法根据介入治疗方法的不同,将40例恶性气道狭窄患者分为两组。A组(22例)使用冷冻联合氩气刀治疗,B组(18例)使用单纯冷冻治疗,评价两组治疗方法的临床疗效及并发症情况。结果 A组患者再通有效率为95.45%,明显高于B组(66.67%),差异有统计学意义(P<0.05);两组患者未见严重不良反应及并发症。结论冷冻联合氩气刀治疗恶性气道狭窄疗效可靠并安全,优于单纯冷冻治疗,值得临床推广应用。

Objective To explore the clinical effect and safety of bronchoscopic cryotherapy combined with argon knife in the treatment of malignant tracheobronchial stenosis. Methods Forty patients with malignant tracheobronchial stenosis in our hospital from January2010 to December 2014 were investigated,and all the patients were divided into group A and group B. 22 cases of group A were treated with bronchoscopic interventional cryotherapy combined with Argon knife,while 18 cases of group B were treated with cryotherapy,then the clinical effects and complications were compared between the two groups. Results The remission rate of group A was 95. 45%,which was better than 66. 67% of group B,and there were significant differences( P < 0. 05). Severe adverse effects and complications were not found in all patients of the two groups. Conclusion Cryotherapy combined with Argon knife in the interventional treatment of malignant tracheobronchial stenosis is effective and safe,so it is worth clinical promotion and application compared with single cryotherapy.