颅脑损伤患者急性胃肠损伤的危险因素分析

Risk factors analysis of acute gastrointestinal injury in patients with brain injury

目的分析颅脑损伤患者继发急性胃肠损伤(AGI)的危险因素。方法回顾分析2010年1月至2013年12月在皖南医学院附属黄山市人民医院重症医学科住院的239例颅脑损伤患者的临床资料,并进行统计学分析。结果 231例患者(96.65%)发生AGI,其中Ⅰ级180例,Ⅱ级49例,Ⅲ级2例;无AGI 8例(3.35%)。合并低灌注153例,合并高血压23例,合并糖尿病4例。格拉斯哥昏迷评分(GCS评分)是AGI发生的高危因素,合并糖尿病、高血压及低灌注等与AGI关联度不高。结论颅脑损伤后,AGI的严重程度与颅脑损伤的严重程度有关,GCS评分是发生AGI的独立危险因素。

Objective To study the risk factors of acute gastrointestinal injury( AGI) in patients with brain injury. Methods A total of 239 cases with brain injury were admitted from January 2010 to December 2013,and statistical analyses of the data from all cases were performed retrospectively. Results 231 cases presented with AGI,180 patients was classified as stage Ⅰ,49 patients in stage Ⅱ and 2 patients in stage Ⅲ; 8 cases had no AGI( 3. 35%). 153 cases were with hypoperfusion,23 cases with hypertension,and 4 cases with diabetes mellitus. The univariate. Glasgow coma scale( GCS) was associated with AGI in patients with brain injury significantly,but hypertention,diabetes mellitus and hypoperfusion were not associated with AGI significantly. Conclusion The patients with brain injury have high incidence of AGI,and the severity of brain injury and AGI are positively correlated. GCS is the independent risk factor for AGI.