个体特异性MRI多期动态增强扫描对原发性肝癌的诊断价值

The diagnostic value of individual specific acquisition for multi-phase dynamic contrast-enhanced MRI in primary hepatocellular carcinoma

目的探讨依据患者自身血液循环差异制订的个体特异性MRI多期动态增强扫描对原发性肝细胞肝癌(HCC)的诊断价值。方法回顾性分析22例HCC患者的影像资料,所有患者均行个体特异性MRI多期动态增强扫描,测取各期感兴趣区的信号强度并绘制时间-信号强度曲线。结果各部位时间-信号强度平均曲线均能描述出注入对比剂后增强达峰并渐行下降的动态过程。HCC病灶在肝动脉中、晚期的信号强度相对增加值为(1.33±0.56)、(1.77±0.50),高于同期肝组织的信号强度相对增强值,差异有统计学意义(P<0.05)。结论个体特异性MRI多期动态增强扫描可以准确、客观地获取各期图像,并对HCC的诊断及血供方式分析具有一定作用。

Objective To explore the value of the individual specific acquisition for multi-phase dynamic contrast-enhanced MRI based on circulation differences in the diagnosis of primary hepatocellular carcinoma. Methods Twenty-two patients with primary hepatocellular carcinoma were enrolled in our study; all cases received the individual specific acquisition for multi-phase dynamic contrast-enhanced MRI scanning; signal intensity of regions of interest at each phase were measured and time-signal intensity curves were drawn. Results The time relative signal intensity curves of each part could describe the dynamic progress of enhancement to peak and followed gradually decline after the injection of contrast agent. The relative signal intensity added values of hepatocellular carcinoma in middle and late arterial phase were( 1. 33 ± 0. 56),( 1. 77 ± 0. 50),higher than the relative signal intensity added value of liver tissue,and there was significant signal difference in middle and late hepatic arterial phase between the hepatocellular carcinoma and liver tissue( P < 0. 05). Conclusion The individual specific acquisition for multi-phase dynamic contrast-enhanced MRI can acquire the whole phases of hepatic enhancement accurately and objectively,which also plays a certain role in the diagnosis of primary hepatocellular carcinoma.