经内镜胆管支架引流术治疗恶性梗阻性黄疸21例

Malignant obstructive jaundice treated by endoscopic biliary stent insertion: An analysis of 21 cases

目的探讨经内镜胆管支架引流术治疗恶性梗阻性黄疸的疗效。方法回顾性分析21例经内镜胆管支架引流术治疗的恶性胆管梗阻性黄疸患者的临床资料。结果 18例患者插管成功,插管成功率为85.71%,其中2例置入金属支架,16例置入塑料支架。成功置入支架的18例患者术后黄疸逐渐消退,皮肤瘙痒等症状明显缓解或消失,血清总胆红素从(230.85±83.81)μmol·L-1下降到术后1周(121.88±52.27)μmol·L-1(P<0.01),转氨酶也显著下降(P<0.01)。结论经内镜胆管支架引流术是姑息治疗恶性梗阻性黄疸的重要手段,疗效确切。

Objective To evaluate the clinical efficacy of endoscopic placement of biliary stents in the management of malignant obstructive jaundice. Methods The clinical data of 21 patients who underwent placement of biliary stents for palliation of malignant biliary obstruction between 2010 and 2013 were retrospectively reviewed. Results The stents were placed successfully in 18 patients( 85.71%). Two cases were successfully embedded with metal stents,16 cases were embedded with plastic stents. The serum level of total bilirubin decreased from( 230. 85 ± 83. 81) μmol·L- 1to( 121. 88 ± 52. 27) μmol·L- 1after treatment( P < 0. 01). This was accompanied by a significant decrease in aminotransferase. Conclusion Endoscopic placement of biliary stent is an effective palliation treatment for malignant biliary obstruction.