Preparation of chitosan–TPP nanoparticles and their physical and biological properties

Over the last few decades,several polymeric nanoparticles using biomaterials have been extensively developed for use as drug delivery systems(DDS)and for other medical applications.Therapeutic nanoparticles have the advantage of controlled drug-targeting delivery and release,which improves the stability,enhances the efficiency and reduces the side effects of the drug[1].Chitosan is a versatile polymer that has been used in drug delivery system as nanoparticles because of biodegradable,biocompatible,and low toxicity[2].