摘要
A series of novel flavonols were synthesized by cyclizing corresponding hydoxy chalcones using Algar flynn Oyamada reaction (1)The synthesized compounds were characterized by various spectrochemical methods including IR, MASS, NMR spectroscopy. Out of 13 compounds screened for antibacterial activity [2], compound VMF 12 (a bromo derivative) showed activity with an IC50value at 0.16μM against S. aureus.
