生物发酵法生产1,3-丙二醇和2,3-丁二醇

Production of 1,3-Propane Diol and 2,3-Butane Diol by Biological Fermentation

1,3-丙二醇(1,3-PDO)和2,3-丁二醇(2,3-BDO)是工业生产中常见的二醇,可以直接由可再生原料经生物转化生成,在化学、能源等方面具有广泛的用途。本文综述并讨论了微生物发酵法生产这两种二醇的进展,重点介绍了生产菌株的改造及发酵过程的优化。

1,3-propane diol(1,3-PDO)and 2,3-butane diol(2,3-BDO)are common diols in the industrial production,they can be generated directly from the bioconversion of the renewable materials,which have a wide range of appealing applications in chemistry and energy.We review and discuss the recent development in the microbial fermentation production of these two diols,especially regarding the transformation of production strains and optimization of the fermentation processes.