Procalcitonin and mid-regional pro-adrenomedullin as promising markers for sepsis diagnosis and prognosis

To the Editor,We read with great interest the recent review by Limongi et al.on sepsis biomarkers[1].Recently,the combined use of two biomarkers,procalcitonin(PCT)and mid-regional proadrenomedullin(MR-pro ADM)has been reported in sepsis diagnosis and prognosis.PCT is a polypeptide produced as a precursor of calcitonin by thyroid C cells normally