摘要
豆科槐属植物苦豆子(Sophora alopecuroides L.)在我国主要分布在西北沙漠地带,主治菌痢及肠炎。苏联学者曾对其化学成分进行了研究。作者从宁夏盐池地区苦豆子花期地上部分,用稀酸渗漉,经阳离子交换树脂提得总生物碱(得率2.66%)。
A new alkaloid named 11-dehydroaloperine was isolated from the leaves and stalks of Sophora alopecuroides L.during flowering.Total alkaloid was obtained by diluted acid percolation and cation-exchange resin,then the new alkaloid was obtained via various polar solvent extraction under various pH value and Al_2O_3 column chromatography.The new alkaloid was proved to be analogous to aloperine through UV,IR,and mass spectrometry.Its structure was further identified by ~1HNMR,^(13)CNMR,~1H-~1H cosy spectrum,NOE as well as by some other chemical methods.
关键词
苦豆子
脱氢苦豆碱
结构
Sophora alopecuroides
△'-dehydroaloperine
