摘要
很多学者对LDR(低剂量辐射)可以在体内及体外培养的细胞中诱导出适应性反应的机理进行了深入的研究,发现适应性反应的诱导与很多因素有关,这些因素包括LDR诱导的DNA修复系统的激活、LDR诱导的基因和蛋白的作用、抗氧化物酶的作用、细胞信号转导以及与p53蛋白有关的细胞周期阻滞的影响等。
Low dose radiation(LDR)can induce adaptive response in vivo and cultured cells.This phenomenon has been confirmed for more than10years.After the discovery,numerous research works on its intrinsic mechanism have been carried out.It was reported that the adaptive response is related to many factors.These factors include the DNA re-pair system induced by LDR,the function of genes and proteins induced by LDR,the function of antioxidant enzyme,cel-luar signal transduction and cell-cycle delay relation to p53and so on.
出处
《国外医学(放射医学核医学分册)》
2002年第3期127-130,共4页
Foreign Medical Sciences(Section of Radiation Medicine and Nuclear Medicine)