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微分化急性髓系白血病细胞化学及免疫表型研究

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摘要 目的研究微分化急性髓系白血病 (AML MO)细胞化学及细胞免疫表型。方法选河北医科大学第二医院血液室确诊的AML MO 3例 ,骨髓涂片经瑞 姬混合染色及免疫细胞化学ABC染色按FAB协作组标准进行分析。结果3例AML MO骨髓涂片形态学符合FAB协作组标准 ,髓过氧化物酶阳性的原始细胞低于 3% ,T淋巴系单抗CD2 、CD3 、CD7阴性 ,B淋巴系单抗CD1 0 、CD1 9、CD2 2 阴性 ,巨核系单抗CD41 阴性 ,可除外淋巴系和巨核系白血病。结论骨髓细胞形态学、细胞化学及免疫表型是诊断AML MO的主要依据。采用多种单克隆抗体同时染色血细胞及进行多参数分析 ,有利于检测单个细胞多种抗原表达 ,使AML
出处 《医学综述》 2002年第7期433-434,共2页 Medical Recapitulate
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