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A型肉毒毒素保护性抗原基因在大肠杆菌中的表达与鉴定 被引量：2

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作者 王慧 荫俊 侯晓军 宋伟
机构地区 军事医学科学院微生物流行病研究所微生物检验中心毒素实验室
出处 《中华微生物学和免疫学杂志》 CAS CSCD 北大核心 2002年第4期453-454,共2页 Chinese Journal of Microbiology and Immunology
基金 全军医药卫生科研基金资助项目 ( 98M136和0 1MB0 5 9)
关键词 肉毒毒素 基因表达 基因鉴定 A型肉毒毒素保护性抗原基因 大肠杆菌
分类号 R346 [医药卫生—基础医学]
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参考文献2

二级参考文献8

  • 1[1]THOMAS B,HISAO K,MICAELA W,et al. The complete sequence of b otulinum neurotoxin type A and comprison with other Clostridial neurotoxins[J ]. The Journal of Biological Chemistry, 1990, 265(16):9153-9158.
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  • 8刘怀田，军事医学科学院院刊，1996年，20卷，4期，58页

共引文献5

同被引文献10

  • 1Woodward LA, Arimitsu H, Hirst R, et al. Expression of HC subunits from Clostridium botulinum types C and D and their evaluation as candidate vaccine antigens in mice. Infect Immun, 2003, 71 (5): 2941-2944.
  • 2Arimitsu H, Lee JC, Sakaguchi Y, et al. Vaccination with recombinant whole heavy chain fragments of Clostridium botulinum type C and D neurotoxins. Clin Diagn Lab lmmunol, 2004, 11(3): 496-502.
  • 3Pier CL, Tepp WH, Bradshaw M, et al. Recombinant holotoxoid vaccine against botulism. Infect Immun, 2008, 76 ( 1 ): 437-442.
  • 4Clayton J, Middlebrook JL. Vaccination of mice with DNA encoding a large fragment of botulinum neurotoxin serotype A. Vaccine, 2000, 18(17): 1855-1862.
  • 5Holley JL, Elmnre M, Mauchline M, et al. Cloning, expression and evaluation of a recombinant sub-unit vaccine against Clostridium botulinum type F toxin. Vaccine, 2000, 19(2-3): 288-297.
  • 6Swaminathan S, Eswaramoorthy S. Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B. Nat Struct Biol, 2000, 7(8 ): 693-699.
  • 7[1]Han- chung wu, Chia - tsui yeh, Yue - ling huang, et al. Characterization of Neutralizing Antibodies and Identification of Neutralizing Epitope Mimics on the Clostridium botulinum Neurotoxin Type A[ J ]. American Society for Microbiology, 2001,67 (7): 3201 - 3207.
  • 8[3]Oguma K, Fujinaga Y, Inoue K. Structure and function of Clostridium botulinum toxins[ J ]. Microbiol Immunol, 1995,39(3) :161 - 168.
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  • 10[5]Daphne E. THOMPSON . The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene[J ]. Eur. J. Biochem, 1990,189:73 - 81.

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中华微生物学和免疫学杂志
2002年 第4期

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