N-乙基-α-甲基-3-(三氟甲基)苯乙胺的合成

Study on the Synthesis of N - ethyl - α - methyl - (Trifluoromethyl) Aminoethylbenzene

研究了间三氟甲基苯丙酮、一乙胺、氢气在雷尼镍催化下发生氢胺化反应,反应转化率达到68%,制得N-乙基-α-甲基-3-(三氟甲基)苯乙胺,产品结构经1HNMR和IR分析证明与预期结构相符.

The reaction of (3 - trifluoromethyl) - 3 - phenyl - propane - 2 - one and H2, ethylamine under the cata-lysting of Raney was studied, and the yield is about 68%. The product is N - ethyl - α - methyl (trifluoromethyl) aminoethylbenzene, and its chemical elements was confirmed by IR, 1H - NMR.