摘要
为了研究运动疲劳和运动性蛋白尿的发生机理，３０只ＳＤ大鼠随机分成４组，即对照组、运动即刻组、运动后１ｈ组和运动后２４ｈ组，测定不同时相肾脏组织匀浆丙二醛（ＭＤＡ）、游离巯基和Ｎａ＋－Ｋ＋－ＡＴＰａｓｅ的变化，旨在探讨力竭性运动引起的氧化应激时肾功能的影响。研究结果提示，大鼠力竭性游泳运动可导致肾组织匀浆脂质过氧化水平提高，巯基含量下降，Ｎａ＋－Ｋ＋－ＡＴＰａｓｅ活性下降，进而使肾功能异常，这些可能是运动性疲劳和运动性蛋白尿发生的重要原因之一。
In order to Study the mechanisms of exercise - induced exhaustion and porteinuria, the experiment was de- signed to investigate exhaustive exercise - induced oxidative stress on the functions of kidney tissue. 30 male Sprague - Daw- ley rats were randomly divided into four groups, and the changes were measured that tha content of MDA、Free - SH and Na+ - K+ - ATPase activity in the kidney tissue in the different phases were observed. The findings are shown that exhaus- tive swimming can lead to an increase of kidney tissue liPid peroxidation, a decrease of the Free - SH contents and the ac- tivity of Na+ - K+ - ATPase of kidney tissue the changes results in anormality of kidney functions. It might be one of the important reasons of exercise - induced exhaustion and porteinuria.
出处
《肇庆学院学报》
2001年第2期117-120,共4页
Journal of Zhaoqing University
