种子盐溶球蛋白的结构特征

Structural characterization of salt-soluble seed globulin

种子球蛋白一直是人类食物的主要来源。随着对种子球蛋白药理作用认识的不断深入 ,近年来研究重点已从单纯的序列转向结构的研究。种子球蛋白二级结构 (如α-螺旋和β-折叠 )存在较大程度的相似性 ,具有较大的保守性且与蛋白质的特殊功能关系密切 ;而三级结构之间差异明显 ,属易变异区 。

Seed globulins have long been the major source of plant proteins for human being.Along with the understanding the pharmaceutical function of seed globulins,researchers have paid more attention on structure than on primary sequence in recent years.The secondary structures of seed globulins (i.e.α helix and β sheet) share many similarities and are highly conserved,which related with specific functions closely;however obvious differences were observed in variable tertiary structures involved in general functions.