脉压与脑卒中发生的临床研究

Relation Between Pulse Pressure and Acute Stroke

目的 通过对脑卒中患者的脉压分析 ,了解脉压增大是否与脑卒中的发生有关。方法 将我院 5年来住院治疗的 90 7例脑卒中患者分为缺血性脑卒中和出血性脑卒中组 ,并随机选取同期来我院的体检人员 10 0 0例为对照组 ,分析三组人员的脉压差。结果 脉压的增大与脑卒中的发生呈正相关。在缺血性脑卒中组 ,脉压最大的分布区域在70～ 79mmHg ,占 2 7.7%;出血性脑卒中组脉压最大的分布区域在 70～ 79mmHg ,占 2 5 7%;对照组脉压最大的分布区域在 5 0～ 5 9mmHg ,占 2 8 5 %。显示脉压大于 70mmHg脑卒中发生的频率较高。年龄的增大与脉压有一定的关系 ,但三组的同年龄分组比较 ,脑卒中组的脉压水平明显高于对照组 ,直线回归系数有显著差异。三组人员中的高血压患者的脉压分析 ,缺血性脑卒中组的脉压值为 77± 12 4mmHg ;出血性脑卒中组的脉压值为 76± 17 6mmHg ;对照组的脉压值为 5 9± 13 5mmHg。与对照组比较不论是缺血性脑卒中组还是出血性脑卒中组P值均 <0 0 5。结论 脉压的增大与脑卒中的发生有关 ,是引起脑卒中发生的重要危险因素。

s: Obsjective The purpose of present study was to analyze the relation between pulse pressure and acute stroke in the patients with hypertension. Methods 907 in-patients with acute stroke were divided into two groups, ischemic and hemorrhagic group, The other 1000 patients were selected randomly from individuals for routine health examination in our hospital. Results 48.31% of the ischemic group were hypertensive with pulse pressure 77±12.4 mmHg, 58.73% of the hemorrhagic group were hypertensive with pulse pressure 76±17.6 mmHg. While in the control group, only 13.5% were hypertensive and their pulse pressure were 59±13.5 mmHg. Both in the ischemic and hemoyyhagic group,pulse pressure were higher than that of controls (P<0.05). The maximal pulse pressure 70～79 mmHg was found in the 27.7% patients of the ischemic group and 25.7% of the hemorrhagic group. Conclusion Higher pulse pressure was associated with stroke. Pulse pressure may be an important risk factor of stroke.