原发性高血压患者24h平均脉压与左室肥厚的相关性探讨

Relationship Between Average 24-hour Ambulatory Pulse Pressure and Left Ventricular Hypertrophy in Essential Hypertension

目的 探讨原发性高血压患者 2 4h平均脉压与左室肥厚的关系。方法 将 5 8例原发性高血压患者分成两组 -左室肥厚 (LVH)组和非LVH组 ,进行 2 4h无创性动态血压监测。结果 ①两组 2 4h平均脉压 (PP)有显著差异 (P <0 .0 1) ,偶测PP(P <0 .0 5 ) ,LVH组显著高于非LVH组 ;②两组 2 4h平均PP及偶测PP均与左室后壁厚度相对室壁厚度呈正相关。结论 原发性高血压患者脉压增大是导致左室肥厚的相关因素之一 ,2

Objective To investigate the relationship between average 24 hour ambulatory pulse pressure (PP) and left ventricular hypertrophy(LVH).Methods Ambulatory blood pressure monitoring (ABPM) was done in 58 hypertensive patients,which were divided into two groups-one group with LVH and the other without LVH.Results (1)The average 24-hour ambulatory PP ( P <0.01) and the clinic PP ( P <0.05) were significantly increased in the group with LVH than that in the group without LVH.(2)A positive correlation was found between the left ventricular posterior wall thickness (LVPWth) and relative ventricular wall thickness (RWT) and the average 24-hour ambulatory PP ( P <0.01),as well as between LVPWth and RWT and the clinic PP ( P <0.05).Conclusion The elevated PP is a risk factor related to the LVH in essential hypertension,but the significance of the average 24-hour PP is higher than clinic PP in predicting LVH.