^(125)I“籽”永久性组织间植入治疗胸部恶性肿瘤

Permanent Interstitial Implantation of ^(125) Iodine Seed for Thoracic Malignant Tumours

目的 观察12 5I“籽”源组织间照射治疗胸部恶性肿瘤的疗效。方法 将12 5I“籽”放射源植入到靶组织内治疗 6例胸部恶性肿瘤 ,其中肺癌伴广泛纵隔淋巴结及胸壁转移 2例 ,肺Pancoast瘤 3例 ,纵膈恶性神经鞘瘤 1例。结果 随访 6月～ 1年 ,6例均取得较满意的近期疗效 ,未发现术后血象明显降低或其他放射损伤症状 ,局部症状控制满意 ,无12 5I“籽”脱落及游走等并发症。结论 12 5I“籽”永久性组织间植入对术中不能完全切除的胸部恶性肿瘤近期疗效满意 ,可控制局部复发 。

Objective To observe effect of 125 Ioidne seed on interstitial brachytherapy of patient with thoracic malignant tumour.Methods 125 Iodine seed were inserted into the target tissue and permanent left there for brachytherapy in 6 cases of thoracic malignant tumours, which including lung cancer, Pancoast's tumour, mediastinal malignant schwannoma.Results All cases were rehabilitated shortly after operation.The implanted lesions remained controlled now and in dead patients. No radiation-related and 125 Iodine seed -related complications occurred.Conclusion Brachytherapy by implantation of 125 Iodine seeds of remained tumour tissue in patients with thoratic malignant tumor after operation has a satisfactory outcome. This therapy can contro local recurrent of thoracic malignant tumour. But the results in long term should be studied further.