摘要
肌注人参(根)皂甙或人参茎叶皂甙50mg/kg,一周均能明显对抗环磷酰胺所致小鼠免疫器官重量减轻,血清特异性抗体水平下降及淋转功能降低,并使其恢复接近正常对照水平,使地塞米松所致小鼠腹腔巨噬细胞吞噬功能下降和血中ANAE^+淋巴细胞比率降低提高到正常水平,促进抗体生成作用,人参(根)皂甙比人参茎叶皂甙更强。
The effects of SLG on the immune function of normal and immune-suppressed mice were investigated. The results showed that SLG (50mg/kg, im) could correct the suppressive effect of cyclophosphamide, dexamethasone or prednisolone on spleen and. thymus weight, serum specific antibody level and lymphocyte transformation. SLG could also improve the phagocytic activity of peritoneal macrophages and enhance peripheral blood ANAE+-lymphocyte ratio of mice. No obvious effect of SLG on the normal mice were observed except that it could increase the antibody level of normal mice. The results implicate that SLG may have some immunomodulatory effect.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1991年第2期126-129,共4页
Chinese Journal of Pathophysiology
