丹参粉针治疗不稳定型心绞痛临床观察

Clinical Observation on Patients with Unstable Angina Pectoris Treated with Salvia Miltiorrhiza Injection

目的观察丹参粉针治疗不稳定型心绞痛(UAP)的临床疗效。方法将UAP患者82例随机分为两组,治疗组在对照组西医常规治疗基础上加用丹参粉针静滴。1疗程后,分别观察两组心绞痛发作频率及硝酸甘油用量的变化;观察静息心电图、血液流变学指标和SOD、LPO改变情况。结果治疗组在总有效率、心绞痛被控制所需时间、改善异常心电图及血液流变性、调整LPO及SOD水平、减少硝酸甘油用量等方面均优于对照组(P均<0.05)。结论在西医常规治疗基础上加用丹参粉针对UAP的疗效优于单纯西医常规治疗。

Objective:To observe the effects of salivia miltiorrhiza injection to patients with unstable angina pectoris(UAP).Methods :82patients of UAP were di-vided into treatment group(42case)and control group(40case)randomly.The control group was only given with routine treatment,while the treate d group was given with salvia miltiorr hiza injection besides roution trea tment for15days.The difference of angina pectoris occurring frequency,using am ount of nitroglycerin,ECG,blood rheolo gy,the concentrations of SOD and LPO were observed.Results:In treatment group,the efficiency,the mean time of angina pectoris controlled,the imp rovement of abnomal ECG and blood rhe-ology,the activity of SOD increased and the concentration of LPO decreased,decreasing amount of nitroglycerin,are all better significantly than t hose in control group(P<0.05).Conclusion:Salvia miltiorrhiza injection is effec-tive to UAP.The effects of tradition al chinese medicine combined with western medicine are better than western medicine only.