围绝经期妇女的记忆商与雌激素及补肾中药之间关系的临床研究

Clinical Study on Relationship between Memory Quotient, Estrogen and Chinese Nourishing Kidney Herbs in Perimenopausal Women

目的:探讨围绝经期综合征患者和围绝经期健康妇女的记忆商和雌激素水平,比较雌激素类药物和补肾中药对提高记忆力的作用。方法:用补肾中药更年青胶囊和雌激素类药物分别治疗围绝经期综合征患者56例（中药组32例,西药组24例）,并进行治疗前后记忆商测试。雌激素水平测定及健康妇女记忆商和雌激素水平测定。结果:中药组和西药组治疗后的记忆商、雌二醇均明显提高,卵泡刺激素明显下降（P<0.05）;与健康人组比较差异无显著性,西药组和中药组疗效相同。结论:记忆力下降与体内雌激素水平降低有关,雌激素及补肾中药治疗能改善大脑功能,增强记忆力。

Objective: To explore the memory quotient and hormone level in women with perimenopausal syndrome and healthy women in perimenopausal period, and the effect of estrogen and Chinese nourishing Kidney herbs (CNKH) on memory. Methods: Fifty-six women of perimenopausal syndrome were treated with estrogen (n = 24) and CNKH (n = 32) respectively. The changes of memory and estrogen level before and after treatment were determined and compared with those in healthy women. Results: The memory quotient (MQ) and estrogen level increased and follicule-stimulating h&rmone (FSH) level decreased significantly after treatment in both groups (P<0.01), these parameters approached to those in healthy women. The difference of therapeutic effect between the two treated group was insignificant (P>0.05). Conclusion: The decrease of memory is related to the lowering of estrogen level, CNKH could improve the brain function and enhance memory.