自拟消风散治疗血虚风燥型慢性荨麻疹的临床疗效观察

Clinical Observation of Self-prescribed Xiaofeng Powder for Treatment of Chronic Urticaria with Blood Deficiency and Wind Dryness Syndrome

【目的】观察自拟消风散治疗血虚风燥型慢性荨麻疹的临床效果,并与左西替利嗪进行疗效比较。【方法】将160例血虚风燥型慢性荨麻疹患者随机分为治疗组和对照组各80例。治疗组以自拟消风散加减治疗,对照组用盐酸左西替利嗪口服液治疗,疗程均为4周,比较2组患者的临床疗效及复发率。【结果】(1)治疗4周后,治疗组的的综合疗效显著优于对照组,差异有统计学意义(Z=-4.059,P<0.001)。(2)治疗后,2组均能改善瘙痒、风团、心烦易怒、口干等症状以及减少复发率,且治疗组的作用优于对照组,差异均有统计学意义(P<0.01)。【结论】自拟消风散在治疗血虚风燥型慢性荨麻疹方面疗效确切,与盐酸左西替利嗪口服液治疗比较,在改善患者瘙痒、心烦易怒、睡眠、口干等症状以及减少复发率方面更有优势。

Objective To observe the therapeutic effect of self-prescribed Xiaofeng Powder （XP） for the treatment of chronic urticaria with blood deficiency and wind dryness syndrome, and to compare the effect of XP to that of levoeetirizine. Methods One hundred and sixty qualified patients were randomly divided into 2 groups, 80 cases in each group. The treatment group was given oral use of modified XP, and the control group was given oral use of levoeetirizine hydroehloride oral solution, treatment lasting for 4 weeks. After treatment, the therapeutic effect and recurrence rate of both groups were evaluated. Results After treatment, the therapeutic effect of the treatment group was superior to that of control group （Z=-4.059, P〈0.001）, and the treatment group had better effect than the control group on decreasing the recurrence rate and on relieving symptoms such as pruritus, wheal, irritability and dry mouth （P〈0.01） . Conclusion XP is effective for the treatment of chronic urticaria with blood deficiency and wind dryness syndrome, and has the advantages of decreasing the recurrence rate and relieving symptoms of itching, irritability, insomnia, and dry mouth as compared with levocetirizine hydrochloride oral solution.