置管引流大剂量乙醇分次硬化治疗肝肾巨大囊肿的新探索

Catheter Drainage and Large- dose Alcohol by Several Times with Hardening of the New Exploration for the Treatment of Liver and Kidney Huge Cyst

目的探讨经皮穿刺置管引流及大剂量乙醇分次硬化治疗肝肾巨大囊肿的疗效及安全性。方法选取最大直径≥8 cm肝脏或肾脏巨大囊肿,囊肿患者分为两组,对照组35例,采用PTC针穿刺一次性大剂量无水乙醇囊内冲洗法。研究组38例,采用置管引流分次大剂量无水乙醇冲洗法。两组治疗方法比较术中术后不良反应的发生率。术后随访一年,观察囊肿直径变化并比较两组间的疗效差别。结果置管引流分次硬化治疗组术后疗效优于对照组,术中术后不良反应发生率低于对照组。结论应用置管引流大剂量乙醇分次硬化治疗肝肾巨大囊肿疗效更显著,更安全可靠。

Objective To investigate the efficiency and safety of Catheter drainage and large-dose alco-hol by several times for hardening treating of liver and kidney huge cyst. Methods Patients with huge cyst（≥8cm）were divided into two groups. The control group with 35 patients was treated with PTC needle puncture one-time large-dose absolute alcohol rinse. The research group with 38 patients were treated with Catheter drainage and large-dose absolute alcohol by several times rinse. The incidence of intraoperative and postoperative adverse reactions were compared between the two groups. Diameter of cyst as a parameter of efficiency was recorded and compared between two groups during 1 year postoperative follow-up visit. Results Incidence of intraoperative and postoperative adverse reaction was lower than control group,which indicates that the methods used in research group was much more efficient in treating hepatic cyst than that used in the control group. Conclusions Catheter drainage and large-dose alcohol by several times for the hardening treatment of liver and kidney huge cyst has ob-vious therapeutic effect,safety and reliability.