透明质酸钠加雌激素对预防人工流产术后子宫内膜炎作用研究

Study on the effect of sodium hyaluronate combined with estrogen in preventing the postoperative endometritis of patients with induced abortion

目的探讨及研究透明质酸钠加雌激素在预防人工流产术后子宫内膜炎中的作用。方法选取2012年1月~2013年12月该院诊治的200例人工流产患者为研究对象,将其随机分为A组（透明质酸钠联合雌激素组）、B组（透明质酸钠组）、C组（雌激素组）和D组（常规干预组）,每组50例,然后将4组患者治疗前后的子宫内膜炎症状评分、血清及宫颈分泌物炎症指标进行比较。结果 A组患者治疗后1周及3周的各项症状评分均低于B组、C组及D组,血清及宫颈分泌物炎症指标水平也均低于B组、C组及D组,同时B组与C组均低于D组,均P〈0.05,但B组及C组之间则差异无统计学意义,均P〉0.05。结论透明质酸钠在预防人工流产术后子宫内膜炎中的作用较好,配合雌激素可达到更好地控制炎症状态的目的。

【Objective】To study and investigate the effect of sodium hyaluronate combined with estrogen in preventing the postoperative endometritis of patients with induced abortion. 【Methods】 200 patients with induced abortion in our hospital from January 2012 to December 2013 were the study object, and they were randomly divided into group A（sodium hyaluronate combined with estrogen group） 50 cases, group B（sodium hyaluronate group） 50 cases, group C（estrogen group） 50 cases and group D（conventional intervention group）50 cases, then the endometritis symptom score, serum and cervical secretions inflammatory indexes of four groups before and after the treatment were compared. 【Results】 All the symptoms score of group A at first and third week after the treatment were all lower than those of group B, group C and group D, the serum and cervical secretions inflammatory indexes were all lower than those of group B, group C and group D, and the evaluation items of group B and group C were all lower than those of group D, all P〈0.05, while the evaluation indexes of group B and group C had no significant differences, all P〉0.05. 【Conclusion】 The effect of sodium hyaluronate in preventing the postoperative endometritis of patients with induced abortion is better, and combined with the estrogen can achieve the goal of better controlling the inflammatory state of patients.