益赛普联合复方风湿宁片用于难治性强直性脊柱炎的疗效研究

Study on effect of etanercept combined with compound fengshining tablet for refractory ankylosing spondylitis

目的分析益赛普联合复方风湿宁片治疗难治性强直性脊柱炎的临床效果。方法将2011年2月—2012年9月收治的60例难治性强直性脊柱炎患者,随机分为治疗组和对照组。对照组采用益赛普治疗,治疗组在对照组的基础上联合复方风湿宁片治疗,监测2组患者的观察指标。结果 2组患者的各项指标在治疗后均升高,但治疗组改善更明显(P<0.01)。临床症状缓解的时间分别为(38.1±2.8)d、(67.5±4.2)d,治疗组明显优于对照组(P<0.01)。结论难治性强直性脊柱炎应用益赛普联合复方风湿宁片治疗,能够明显缓解症状、控制复发,疗效显著,值得临床推广应用。

Objective To analyze etanercept rheumatoid joint compound tablets for the treatment of refractory ankylosing spondylitis clinical effect. Methods February 2011～2012 September 60 treated patients with refractory ankylosing spondylitis patients were randomized to two groups of 60 patients in the treatment group and the control group,the control group etanercept treatment group in the control group tablets treatment of rheumatoid joint compound, based on the monitoring of the two groups of patients with observed indicators. Results The two groups of various indicators of patients were increased after treatment, but the treatment group improved more significantly. Clinical remission time was（38.1±2.8）d,（67.5±4.2）d, the treatment group also improved more significantly, with a statistically significant（P〈0.01）.Conclusion The treatment of refractory ankylosing spondylitis applied joint compound etanercept treatment of rheumatoid tablets, can significantly alleviate symptoms, control relapse, a significant effect should be widely applied.