中药“抗生素”临床应用思考

Clinical Application of Chinese Medicine of Antibiotics

抗菌药物的不合理应用及细菌的耐药现象已成为我国医疗卫生事业所面临的两大挑战,随着"限抗令"的出台,化学类抗菌药物的临床使用受到不同程度的影响,中药具有抗菌作用的药物越来越受到临床医生的关注。具有抗菌作用的中药多为植物,本身并不是从微生物中提取出来的,所以它与抗生素有本质的区别,虽然部分中药具有抑制或杀灭微生物的作用,但其作用强度仍然逊色于抗生素,加上中药的作用机制不甚明确,因而中药"抗生素"不能代替抗生素。相对于抗生素来说,中药"抗生素"并没有常见的耐药菌,这也体现了中药治疗疾病的整体效应。

The rational use of antimicrobial agents and bacterial drug resistance phenomenon has become the two major challenges facing China＇s medical and health undertakings,as the resistance to limit,chemical class of antimicrobial drugs for clinical use is affected by the different degree,the antimicrobial effect of traditional Chinese medicine drugs more and more attention from clinical doctors. Antimicrobial effect of traditional Chinese medicine for more plants,itself is not extracted from microorganisms,so it have substaintial distinction with antibiotics,although some Chinese traditional medicine can inhibit or kill the role of microorganisms,but its strength is still inferior to the antibiotics,and not very clear,the mechanism of action of traditional Chinese medicine and traditional Chinese medicine ＂antibiotics＂ is no substitute for antibiotics. Relative to antibiotics,Chinese traditional medicine ＂antibiotics＂ has no common drug-resistant bacteria. This also reflects the overall effect of traditional Chinese medicine to treat disease.