幽门螺杆菌根治率与慢性胃炎中医证型的相关性研究

Correlation of TCM syndromes and H.pylori eradication rate of chronic gastritis patients

目的通过聚类分析法分析幽门螺杆菌(helicobacter pylori,H.pylori)根治率与中医证候分型间的联系。方法以137名慢性胃炎并接受根除H.pylori治疗患者为研究对象,应用Kmeans聚类分析法对这些患者的中医证候学资料进行分析。结果通过聚类分析方法,可以将患者分为4类:肝胃不和型,脾胃虚弱型,肝郁气滞兼有脾虚型,脾胃湿热兼有阴伤型。其中脾胃湿热兼有阴伤型中H.pylori根治率最低,为50%,肝郁气滞兼有脾虚型根治率最高,为90.9%。结论慢性胃炎不同证型患者中的H.pylori根治率不同。

Objective Analyzing correlation between TCM syndromes and H. pylori eradication rate of chronic gastritis patients by cluster analysis. Methods We identified 137 chronic gastritis cases that re-ceived H. pylori eradication treatment as research objects and analyzed their TCM syndromes and H. pylori e-radication rate with K-means cluster analysis. Results According to the result of cluster analysis,patients were divided into four categories：Liver-stomach disharmony type,Weak stomach type,Both liver qi stag-nation and stomach deficiency type,Both stomach hygropyrexia and yin injury type. Among these types. H. pylori eradication rate of both stomach hygropyrexia and yin injury type is the lowest （50%）,eradica-tion rate of both liver qi stagnation and stomach deficiency type is the highest （90.9%）. Conclusion Pa-tients with chronic gastritis with different TCM syndromes type have different H. pylori eradication rate.