大连市某院2012年临床输血不良反应回顾性分析

A retrospective analysis of clinical adverse transfusion reactions in a hospital of Dalian in 2012

目的回顾性调查分析本院输血不良反应的发生情况,为输血不良反应的有效预防和处理提供参考。方法通过本院2012年所有住院患者用血信息统计,包括输血成分,输血量和输血不良反应,调查发生非传染性输血反应的患者输血信息,分析引起输血不良反应的原因。结果在接受输血治疗的21 224名患者中,共输血25 638例,存在131例非传染性输血反应,输血不良反应率为0.511%;男、女非感染性输血不良反应的发生率比较差异有统计学意义(P<0.05),有输血史与无输血史的比较差异有统计学意义(P<0.05)。不同血液成分的输注均可导致输血不良反应的发生。发生在2 h内输血不良反应占59%。结论输血治疗时,加强输血过程的监测,发生输血不良反应时,对症及时处理。同时要提倡自体输血,避免输血不良反应发生。

Objective The reports of adverse transfusion reactions in our hospital were studied retrospectively,to provide reference for preventing and managing suspected adverse transfusion reactions. Methods The medical records of all patients who received transfusion in our hospital in 2012 were searched and analyzed. The records included component transfused,units of blood transfusion and adverse transfusion reactions. The records of patients with non-infectious transfusion reactions were investigated and the causes of transfusion reactions were analyzed. Results Among the 21 224 patients who recieved transfusion,there were 25 638 cases of blood transfusion and 131 cases of non-infectious transfusion reactions. The incidence of adverse transfusion reactions is 0. 511%. There were significant differences between the incidences of men and women（ P 〈0. 05）. There were significant differences between patients with transfusion history and paitents without transfusion history（ P〈 0. 05）. Transfusion of different blood components may lead to the occurrence of adverse transfusion reactions. 59% of adverse transfusion responses occurred within 2 hours. Conclusion We need to strengthen monitoring of blood transfusion and advocate autologous blood transfusion for avoiding adverse transfusion reactions.