海洋微生物抗菌活性物质研究进展

Research Advances of the Antibiotics Substances of Marine Microorganisms

海洋微生物是次级代谢产物的生产者中很重要的一类,目前发现了许多新的具有一系列生物活性的物质,其活性主要包括:抗菌、抗肿瘤、抗炎以及细胞毒作用等。目前由于抗生素类药物的滥用,使得耐药菌的种类越来越多,因此从海洋微生物中寻找对耐药菌敏感的化合物成为目前研究的热点,本文旨在对近3年海洋微生物抗菌活性成分研究进行以下概括。

Marine microorganisms was a important group among the producers of secondary metabolite. There were many novel bioactive substances discovered so far, which activity including： antibacterial, antitumor, antiinfl ammatory and cytotoxicity and so on. Now the kinds of drug-resistant bacteria have continued increasing which were caused by the abuse of antibiotic medicines. Therefore, fi nding drug-resistant bacteria sensitive antimicrobial compounds in marine microorganisms became the hotspot of recent research. The studies on antibiotics substances of marine microorganisms of recent three years were summarized below.