清洁灌肠佐治新生儿高胆红素血症的临床观察

Effect of Cleansing Enema--assisted Therapy on Neonatal Hyperbilirubinemia

目的观察清洁灌肠佐治新生儿高胆红素血症的效果。方法对我科150例高胆红素血症患儿随机分为对照组72例,观察组78例。所有患者给予光照疗法以及药物(白蛋白、肝酶诱导剂)等综合治疗,观察组在此基础上佐以清洁灌肠。结果两组治疗后血清结合胆红素(S-DBIL)和间接胆红素(Indirect bilirubin)水平比较,观察组明显低于对照组,P<0.05。结论清洁灌肠佐治新生儿高胆红素血症加速血清胆红素水平的下降,有效提高了治疗效果。

Objective To investigate the clinical effect of cleansing enema-assisted therapy on neonatal hyperbilirubinemia. Methods 150 cases of neonatal hyperbilirubinemia were divided into treatment group with 78 cases and control group with 72 cases. All the patients were treated by routine light therapy with medicines（albumin and liver enzyme inducers）. Treatment group was supplemented with cleansing enema. Results The levels of S-DBIL and indirect bilirubin in treatment group were signifi cantly lower than control group＇s. The differences were statistical signifi cant（P〈0.05）. Conclusion Cleansing enema-assisted therapy accelerates the decrease of serum bilirubin level in neonatal hyperbilirubinemia, and effectively improves the treatment effect.