呼肠孤病毒与链球菌混合感染雏鸭的病理学研究

Pathological Studies of Duck Reovirus Co-infected with S. gallolyticus subsp. pasteurianus

以携带有鸭源呼肠孤病毒(DRV)的7日龄雏鸭为试验动物,人工感染解没食子酸链球菌巴氏亚种(S.gallolyticus subsp.pasteurianus)AL101002菌株,旨在建立混合感染的病理模型。采用病理学研究手段,观察感染雏鸭的临床症状、病理变化及组织学病理变化。研究结果表明,雏鸭于感染后1 d出现死亡,感染后3 d表现出典型临床症状,死亡率为50%;剖检病理变化主要表现为脾脏表面灰白色坏死灶,质地坚实,心包膜炎和肝包膜炎,脑膜充血严重;组织学病理变化主要表现为脾组织坏死、包囊的形成、心肌炎、脑膜炎等。

7-day-old ducklings with duck reovirus （DRV） were infected with S. gallolyticus subsp. pasteurianus （AL101002） to study its clinical symptoms, anatomical and histological pathology changes. The results showed that the death of ducklings occurred at 1 dpi and typical clinical symptom could be observed at 3 dpi with the mortality of 50%. The anatomical observation showed hoary necrosis foci occurred in the spleen and felt character of solid, pericarditis, perohepatitis, and seriously meninx congestion. The histological pathology mainly presented the necrosis of spleen with cyst, myocarditis and meningitis.