小儿幽门螺旋杆菌感染与缺铁性贫血的相关性分析

Correlation between Helicobacter Pylori Infection and Iron Deficiency Anemia in Children

目的:分析并探讨小儿幽门螺杆菌感染与缺铁性贫血的相关性。方法:选择2012年2月至2013年2月本院门诊患儿412例,行血常规、血清铁、血清铁蛋白、HP-IgG抗体检测。结果:HP感染患儿IDA26例,IDA患病率为20.4%(26/127),HP未感染患儿IDA19例,IDA患病率为6.7%(19/285)。两者比较差异有统计学意义(x2=17.21,P=0.00)。对比两组患儿MCV、MCH、MCHC指标,差异具有显著性(P均<0.05)。45例IDA患儿中26例有HP感染,感染率为57.8%(26/45),367例非IDA患儿中有101例HP感染,感染率为27.5%(101/367)。两者比较差异有统计学意义(x2=17.21,P=0.00)。结论:HP感染同IDA发病有显著相关性,HP感染可以是导致IDA的原因。

Objective： To analyze and discuss the correlation of Helicobacter pylori infection and iron deficiency anemia of children. Methods： We choose 412 cases hospital outpatient children from February 2012 to February 2013, and test the blood count,serum iron, serum ferritin and HP-IgG antibodies. Results： 26 HP infected children had IDA HP and the IDA prevalence was 20.4%（26/127）, 19 HP-uninfected children had IDA, and the IDA prevalence was 6.7%（19/285）. The difference was statistically significant（x2= 17.21, P = 0.00）. Compared the MCV, MCH, MCHC index of the two groups, the difference was significant（P〈0.05）. 26 out of 45 IDA children had HP infection, and the infection rate was 57.8%（26/45）. 101 out of 367 children with non-IDA had HP infection, and the infection rate was 27.5%（101/367）. The difference was statistically significant（x2= 17.21, P = 0.00）. Conclusion： HP infection and the onset of IDA have significant correlation. HP infection may be the cause of IDA.