宫颈癌调强放射治疗的剂量验证分析

Verification and Analysis of the Dose of Intensity Modulation Radiated Therapy(IMRT) on Cervical Cancer

目的:通过总结比较Eclipse和Xio两个治疗计划系统对宫颈癌调强放疗剂量验证的结果,分析评价宫颈癌调强放疗在临床应用上剂量的准确性。方法:分别用固体水模和二维电离室矩阵Mapcheck、FC65-G指形电离室在定位螺旋CT上进行扫描,断层数据通过网络传输到Eclipse和Xio两个治疗计划系统中建立验证模体。选取2013年1月至5月在本院24例宫颈癌调强治疗患者,在两个TPS(Treatment Planning Systems)上将宫颈癌调强放疗计划移植到模体上,用IBA公司的DOSE1、FC65-G指形电离室模体和Nuclear公司的二维电离室矩阵Mapcheck模体在加速器下进行点剂量和面剂量的采集。结果:Eclipse系统的12位患者随机选取24个照射野3 mm 3%面剂量的γ通过率均值为98.8%,Xio系统的12位患者随机选取24个照射野3mm3%面剂量γ通过率均值为97.7%,二者比较差别有统计学意义(P<0.01)。Eclipse系统的12位患者84个照射野点剂量的误差的均值为1.2417%,Xio系统的12位患者84个照射野点剂量的误差均值为2.4892%,二者比较差别具有统计学意义(P<0.01)。结论:Eclipse和Xio两个治疗计划系统都可以应用于宫颈癌临床调强放疗,但Eclipse系统的准确性优于Xio系统。

Objective： To verify and analyze the dose of intensity modulation radiated therapy（IMRT） on cervical cancer through comparing the Eclipse and Xio systems and evaluate the accuracy of dose of cervical cancer in the clinical application of IMRT.Methods： Solid water phantom and two-dimensional ionization chamber matrix Mapcheck, FC65-G ionization chamber were used in the positioning finger on spiral CT scans, fault data through the network to the Eclipse and Xio treatment planning system to create verification phantom. 24 cases of cervical cancer admitted between January and May 2013 in the hospital were selected and treated with IMRT at two TPS（Treatment Planning Systems）, cervical cancer IMRT plans will be transplanted to the verification phantom, and with the IBA＇s DOSE1, FC65-G ionization finger-chamber and Nuclear company＇s two-dimensional matrix Mapcheck phantom ionization chamber with verification phantom under the accelerator to get point dose and the surface dose. Results： Eclipse system, 12 patients were randomly selected 24 radiation fields 3 mm3% surface dose of γ rate value through 98.8%, Xio system, 12 patients were randomly selected 24 radiation fields 3 mm 3% surface dose γ rate is 97.7%（P 〈0.01）. The mean error of the 12 patients 84 point dose of irradiation fields in Eclipse system was 1.2417%, the mean error of 12 patients 84 point dose irradiation fields in Xio system was 2.4892%（P〈0.01）.Conclusion： Two treatment planning systems could be applied to cervical cancer IMRT, the accuracy of Eclipse system was superior to that of Xio system.